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For people already managing GI side effects with careful dietary adjustments , early dosing can undo weeks of careful management

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Additionally, BPC 157 consistently recovered smooth muscle function, in particular, various sphincters [2,6,10]

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A 2023 retrospective cohort analysis in JAMA Internal Medicine (N=16,922) found that patients on a GLP-1 RA plus an opioid had a 33% higher rate of bowel obstruction-related ED visits compared to patients on a GLP-1 RA alone [5]