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Up-regulation of the PPP flux provides cells with R5P for nucleotide biosynthesis, as well as NADPH for biosynthesis and maintaining redox homeostasis (59, 67, 70)

There were clinical and methodological differences between studies, such as different inclusion criteria, variability in results due to administered medications, and most significantly - different study designs which may have affected the study results

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Discussion The purpose of this study was to investigate long-term (over a year) changes in antioxidant levels following irradiation in vivo