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Talbott, Amare Global, United States Elyas Nattagh-Eshtivani, Mashhad University of Medical Sciences, Iran Mustafa Karakse, Giresun University, Trkiye Updates Copyright 2024 Weichmann and Rohdewald

Lancet 392 , 637649 (2018)

This activation leads to the stimulation of the VEGFR2-Akt-eNOS signaling pathway, enhancing endothelial tube formation and blood flow recovery in ischemic tissues

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Notably, AFG pretreatment enhanced recovery from renal injury by alleviating OS, mediating NF-B-related inflammation, and inhibiting the PI3K/Akt apoptotic signaling pathways