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Findings: Rodent models showed modulation of fat metabolism and support for lean tissue-related signaling

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Glutathione peroxidase 4 (GPX4) utilizes glutathione (GSH) to reduce lipid peroxidation to lipid alcohols, so drugs that target GPX4 or GSH to accumulate lipid peroxides offer the possibility of fighting cancer

50 Other reasons are the differences of the rate of L-carnitine uptake from different tissues, and the variation of storage of L-carnitine among different tissues (hepatic, renal, cardiac, skeletal muscle, and brain)