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Baseline HbA1c in these studies varied from 8.1 to 8.7% (6572 mmol/mol)
These studies provide a better understanding that the composition of gut microbiota differs between benign and malignant tumours compared to normal samples (Fig
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In vivo, Ex-4 has been demonstrated to inhibit prostate cancer cell growth by activating GLP-1R, reducing s-phase kinase-associated protein-2 (SKP2) gene expression, subsequently increasing p27Kip1 (p27) protein levels, and inducing tumor cell cycle arrest [67]