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Hormone therapy carries documented risks including blood clots, stroke, breast cancer, and endometrial cancer, which are evaluated by the treating clinician based on individual patient profile

Indirect calorimetry, a non-invasive technique, allows for the precise quantification of energy expenditure and respiratory quotient, offering a window into the metabolic shifts that occur in T2DM

Both liraglutide and semaglutide activate the same GLP-1 receptor pathway, making simultaneous use medically unsafe and potentially harmful

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Injection Site Reactions: Redness or irritation at the injection site is common but usually resolves quickly

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