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Vitamin B12 shots may not be suitable for people with a history of: sensitivity to vitamin B12 Lebers disease, which affects the optic nerve kidney problems hypokalemia (low potassium levels) deficiencies in other nutrients, particularly folic acid and iron Vitamin B12 injections typically begin to work straight away

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The antibodies also block a critical protein called intrinsic (in-TRIN-sic) factor