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That high discontinuation rate makes it especially important to understand what happens to weight and health risks related to diabetes and heart disease once treatment is discontinued

10 More than 99% of bacterial species belong to the phyla Firmicutes, Bacteroidetes, Proteobacteria, and Actinobacteria, among which Firmicutes and Bacteroidetes dominate in the gut microbiota of healthy hosts

Therefore, with a well selected population that would diminish the 95% confidence interval of relative risk of cardiovascular disease, we suggest that there might be an increased cardiovascular risk in the MTHFR TT mutants when folate status is low