Antioxidant Depletion: In an ironnitrilotriacetic acid rat model of hemochromatosis, renal samples showed increases in reactive intermediates, accompanied by decreased availability of systems that protect against oxidation by iron, such as vitamin E levels, the glutathione system, thiol-specific antioxidants, and superoxide dismutase
Survival signaling without adequate antioxidant protection leaves cells vulnerable
While the parasites are able to take up hemoglobin from the host cell cytoplasm and rapidly metabolize it, human hemoglobin does not contain all the amino acids necessary for P
Superior water-binding performance
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