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For musculoskeletal injuries, the combination is well-supported

In pivotal studies, patients using semaglutide (Wegovy) lost an average of 15% of their body weight over 68 weeks

However, alcohol can worsen nausea and acid reflux, two things GLP-1s already tend to cause

Animal studies have demonstrated that GLP-1 receptor agonists can increase sympathetic nerve activity, particularly to the heart and kidneys

But the molecule has changed

Copper peptide serums with meaningful AHK-Cu concentrations tend to cost significantly more, and the market is less standardized, meaning product quality varies considerably between brands