Beqvez follows CSL Behrings gene therapy Hemgenix, which became the first FDA-approved gene therapy for hemophilia B in November 2022
Most strikingly, multiple trials have now shown that GLP-1 agonists can lead to the resolution of MASH, a severe form of fatty liver disease, without worsening of liver fibrosis, which is a common adverse outcome seen with some current medications
Tirzepatide for Treatment of Obesity (SURMOUNT-1)
Aging individuals: Natural DSIP levels decline with age
G3 (Bethesda) 9(11):36113621 Garca-Ruiz C, Morales A, Ballesta A, Rods J, Kaplowitz N, Fernndez-Checa JC (1994) Effect of chronic ethanol feeding on glutathione and functional integrity of mitochondria in periportal and perivenous rat hepatocytes
BPC-157s extensive publication record (100+ studies) provides the broadest preclinical safety dataset for either compound