Scientific opinion on the relationship between intake of alpha-lipoic acid (thioctic acid) and the risk of insulin autoimmune syndrome
[60] Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.Proc Natl Acad Sci U S A
Front Biosci (Elite Ed) 2013
Guo, Z., Jena, A
Key Points Adrenocorticotropin (ACTH) has a key role in mediating the stress response by acting on a unique membrane receptor in the adrenal gland to stimulate glucocorticoid production Inactivating mutations in the ACTH receptor, or in an accessory protein essential for its expression on the cell surface, cause an inherited syndrome of ACTH insensitivityfamilial glucocorticoid deficiency Disturbances of ACTH-receptor expression or function are often found in benign and malignant adrenal neoplasms Altered responsiveness to ACTH is often present as a secondary phenomenon in several common disorders including depressive illness and septic shock This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 186,36 per year only 15,53 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF
Supports protein synthesis for muscle development