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11,239 It is also possible that GLP-1 therapies mediate beneficial actions via extra cardiovascular GLP-1 signalling, as one study reported that exendin-4 administration in rat femoral arteries did not affect short-term triglyceride exposure-induced endothelial dysfunction

However, the percentage of patients experiencing these adverse reactions were slightly higher than those in the trial of injectable Zepbound

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Avoid the belly button, waistline, or bony areas

GLP-1 agonists were first developed for type 2 diabetes, but several are now approved and widely used for weight management in people without diabetes