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Sulforaphane protects liver injury induced by intestinal ischemia reperfusion through Nrf2-ARE pathway
MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited published safety data Reported well-tolerated in small Russian studies Known interactions GABAergic medications (theoretical unstudied) Benzodiazepines (theoretical additive sedation) Contraindications Pregnancy/lactation (unstudied) Hypersensitivity REGULATORY STATUS FDA Not FDA-approved
Significantly, when combined with immune checkpoint inhibitors or indoleamine 2,3-dioxygenase (IDO) inhibitors, this combinatorial strategy shows strong efficacy in suppressing both the progression of primary tumors and distant metastases, thus presenting remarkable potential for transforming immunologically "cold" tumors into states responsive to immunotherapy [461, 462]
It is naturally produced by the pineal gland and is also available as a supplement to support sleep
Surg Oncol Clin N Am 18 (1): 73-98, viii, 2009
Avoid candies, teas, or dietary supplements that use these herbs
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