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Specification Peptide Name: PT-141 (Bremelanotide) Content: 10 mg lyophilized powder (requires reconstitution) Purity: 99 % (HPLC / MS certificate available) Manufacturing: ISO 9001:2015 & cGMP-audited facility Intended Use: In-vitro laboratory research only Storage & Handling Prior to reconstitution: store 8 C in a dry environment After reconstitution: refrigerate 2 8 C and use within 30 days For long-term preservation: aliquot and freeze at 20 C Avoid repeated freezethaw cycles Compliance Notice Supplied exclusively to qualified professionals for controlled laboratory applications

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Mosenzon O, Blicher TM, Rosenlund S (2019) Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial

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The sensation results from decreased adipose tissue insulation and potential metabolic rate reduction rather than direct drug action on temperature regulation

doi: 10.1007/s00424-017-1955-5 124 ChylikovaJDvorackovaJTauberZKamaradV