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Compared with the NCD group, HFD-fed mice displayed significant enrichment of pro-inflammatory pathways, including cytokinecytokine receptor interaction (NES = 1.712, P = 0.0015), chemokine signaling (NES = 1.895, P = 0.0016), NF-B signaling (NES = 1.609, P = 0.0049), and Toll-like receptor signaling (NES = 1.806, P = 0.0016), confirming a strong activation of innate and adaptive immune processes in adipose tissue (Fig

However, outcomes depend heavily on dosage, treatment frequency, and patient metabolism

In contrast, the size of Mn/TI@mHSA-N remained largely unchanged even after 24 h of ROS exposure (Fig

Gedatolisib shows superior potency and efficacy versus single-node PI3K/AKT/mTOR inhibitors in breast cancer models

Validation of Zebrafish (Danio rerio) Reference Genes for Quantitative Realtime RTPCR Normalization

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