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For all the excitement, the story is still unsettled

People with higher starting body weight tend to lose a smaller percentage of their total weight compared to lighter individuals at the same dose, though they often lose more absolute pounds

Liver fat fraction decreased more in all the combination groups compared with the semaglutide monotherapy group, with the greatest loss seen in the triple therapy group

Adolescents may experience significant pressure from parents, peers, and society to lose weight, potentially compromising their ability to make truly autonomous decisions about treatment

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