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One of the potentially promising approaches, in our opinion, is identifying molecules that have the master-key qualities
To date, clinical trials with inosine have been published and the results have been inconsistent [165,166,167]
The differences between the individual values of GSH content of liver determined in this assay were small, thus, confirming the literature report that GSH content of liver did not change when an animal was pretreated with microsomal drug-metabolizing inducers such as phenobarbitone, 3-methylcholanthrene and polychlorinated biphenyl (Arcolor 1254)
Yet, the available preclinical data also report a favorable safety profile [4, 26, 27, 28]
Common adverse reactions Pain at the injectin site (incidence rate of about 15%), transient diarrhea (8%), and temporary decrease in feed intake (5%)
