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Various structural alterations were made at the N-terminal such as substitution of D-norleucine for L-norleucine, N-acetylation of norleucine, and replacement of norleucine with GABA in order to improve overall stability by reducing susceptibility to aminopeptidases

Liposomes are structures that arise spontaneously from phospholipids

PMID: 30895708

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His central insight: don't try to deliver the molecule, give the cell what it needs to build the molecule itself

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