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10,11 California's spending on the three drugs approved for the weight loss indication increased fourfold from early 2024 to mid 2025, as outlined in Figure 2

Notably, the American Diabetes Association advocates for the utilization of GLP-1 RAs with established cardiovascular benefits in patients diagnosed with type 2 diabetes and concurrent cardiovascular disease

It maximally stimulates muscle protein synthesis, requires more energy to digest (high thermic effect), and provides essential amino acids for physiological functions

Most prior authorization decisions are rendered within three to five business days

For diabetic patients, this poses a substantial threat, as corticosteroids are known to induce hyperglycemia [34]

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