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For a non-gut issue like sciatica, injectable administration is the standard for research to ensure sufficient levels of the peptide reach the target tissues and enter circulation

doi: 10.1093/nutrit/nuy044 [DOI] [PMC free article] [PubMed] [Google Scholar] 66

Increased d-lactic acid intestinal bacteria in patients with chronic fatigue syndrome

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May support skin-related signaling pathways, hydration processes, and cellular communication involved in skin appearance and texture over time with consistent use