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It is natural to speculate whether the inhibition of GS and GCL is an important evolutionary mechanism to keep GSH high, but not too high, in females during the childbearing years

Intramuscular (IM) injections are placed directly into muscle tissue, which has a richer blood supply

Imidazolylacetophenone oxime-based multifunctional neuroprotective agents: discovery and structure-activity relationships

Thus, cationized nanodrugs designed for targeting a desired site may result in an unpredictable distribution throughout the body after intravenous injection, bringing about toxic effects including possible endothelial damage, membrane nephropathy, immune complex-mediated glomerulonephritis, tissue edema or inflammation, and so on 10,16

Xin P, Pan Y, Zhu W, et al

This may support better absorption