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doi: 10.3390/biomedicines11061560 44 SekirovIRussellSLAntunesLCMFinlayBB

2 Materials and methods 2.1 Animals Sixty young male western Albino rats, approximately 3 weeks old, weighing about 6080 g, were obtained from the Experimental Surgery and Animal Laboratory at King Saud University (Riyadh, Saudi Arabia)

Dosing: Weekly subcutaneous injection Maximum dose: 15 mg/week Average weight loss (SURMOUNT-1): 20% over 72 weeks at the highest dose List price: ~$1,086/mo Self-pay: From $399/mo via LillyDirect FDA-approved for: Adults with BMI 30 (or 27 with comorbidities) Side-by-Side Comparison Side Effects: Similar, but Worth Reading Both medications have GLP-1-class side effects: nausea, diarrhea, vomiting, constipation, abdominal pain

This triple-pathway activation profile makes it unlike any other research peptide currently available to UK, US, or European laboratories

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DOI: 10.1038/s44360-026-00108-y The authors report no outside funding