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Alternative treatment options should be discussed if fertility concerns are paramount

2025;27:iii13742

Outcomes and objectives The primary objective was to compare the efficacy of 68 weeks of subcutaneous semaglutide 2.4 mg weekly versus placebo administration, as an adjunct to diet and exercise, on %WL in participants with less than 20% weight loss after primary GB or SG at the end of 68 weeks of treatment

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Phase Phase 2 - Early escalation Weeks Weeks 5-8 Weekly dose 0.5 mg What to expect First meaningful dose

If bloating is severe or accompanied by persistent vomiting, inability to pass gas, or severe abdominal pain, contact your provider immediately for evaluation and guidance