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Results Gut microbiota composition and diversity 16S rRNA gene amplicon sequencing was used to profile the gut microbiota composition of fecal samples from our participants

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A recent study showed that glucose metabolism was dysregulated and that pyruvate supplementation could prevent neurodegeneration in an animal model of glaucoma 31 , suggesting that ATP production from glycolysis is disrupted, and that other energy fuel pathways, such as -oxidation, may be augmented to compensate for the reduction in energy metabolism