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As we age, our natural peptide production decreases, leading to: Formation of fine lines and wrinkles Loss of skin elasticity Increased under-eye puffiness More pronounced dark circles Learn more about the aging process and how we can help reverse its effects

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SIRT1 protects HIF-1 from deacetylation by binding to its inhibitory domain, while inhibiting SIRT2 downregulates fibroblast phosphorylation (45, 46)

Angiopep-2, the ligand of the low-density lipoprotein receptor-related protein enhanced the BBB transcytosis of star-shaped, multibranched poly(l-glutamic acid) nanoconjugates in animals [50]

Taurine also plays important roles in the modulation of intracellular free calcium concentration and in the protection from mitochondrial stress