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It is important to note that topiramate is not licensed for weight management in the UK, though it may be used off-label for this purpose in some circumstances

This bioavailability gap means nasal users require 2-3 times higher doses to achieve equivalent effects - where 1.5mg injection produces desired arousal, nasal spray may need 3-5mg depending on individual absorption

By improving blood sugar control, it helps prevent complications related to diabetes, such as heart disease, kidney damage, and nerve problems

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