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Litwack et al proposed the term Ligandin to cover the proteins previously known as Y proteins

We found that the number of M phase cells in sdn-1(zh20) animals were reduced by ~50% compared to wild-type (Fig

J Mol Histol

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This relatively small GPCR family is characterized by a long extracellular ligand-binding domain stabilized by three disulfide bridges formed by six highly conserved cysteine residues, seven -helical transmembrane domains, universal for all GPCRs and an intracellular C-terminal domain, responsible mostly for receptor internalization due to the presence of multiple phosphorylation sites [22, 23]