Performing motif discovery analysis using HOMER 17 , we found that resolved-accessible DARs are highly enriched for transcription factor (TF) binding motifs of the AP-1 family members, which are known mediators of stress responses, often downstream of cytokine signalling (Extended Data Fig
Food and Drug Administration (2024) 2
Moreover, NRF2 contributes to the anti-inflammatory process by inhibiting the release of pro-inflammatory genes, thus attenuating the pro-inflammatory phenotype that characterizes numerous pathophysiological conditions
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Eye injuries, including corneal ulcers, have been reported in humans and dogs associated with head shaking and splatter following administration
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