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PubMed Central, Truman, Penelope, et al

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Despite the research saying that MOTS-c may be useful as a cancer therapy, other studies have made contradicting claims that it can lead to the development of prostate and breast cancer.43 Our known providers likewise warn that people with an active cancer diagnosis should avoid MOTS-c unless otherwise recommended by their doctor

Investigators have examined its interactions with the hypothalamic-pituitary-adrenal (HPA) axis, stress response systems, and neuroendocrine signaling, as well as its apparent ability to cross the blood-brain barrier under certain experimental conditions

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In fact, research on the combined pill in 2015 showed that semaglutide did not affect the concentration of hormones in the bloodstream