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[5] [6] Similarly, individuals with pre-existing fatigue, anaemia, or other comorbidities may find that GLP-1 therapy temporarily exacerbates their symptoms

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These findings may explain the beneficial effects of selenium supplementation in autoimmune thyroid diseases (181, 194), such as reduced levels of anti-thyroid antibodies, improved thyroid structure and metabolism, and ameliorated clinical symptoms (181, 195)