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When a medication relies on a pen-injector system, such as with the injectable versions of Ozempic and Wegovy, the device itself becomes part of the regulatory and technical challenge

Medication selection also depends on health history, side-effect tolerance, diabetes status, pregnancy plans, medication interactions, insurance, cost, availability, and individual treatment goals

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As a pentapeptide, it is subject to the standard limitations of peptide pharmacokinetics: it cannot be taken orally (destroyed by digestive enzymes), and it requires parenteral administration (subcutaneous injection being the most common route in research settings)