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Compounded semaglutide is prepared by 503A compounding pharmacies for individual patients based on a prescribers order, or by 503B outsourcing facilities producing larger batches under FDA inspection
Clinical studies measuring body composition changes have demonstrated that patients taking FDA-approved anti-obesity medications experience reductions in both subcutaneous abdominal fat (the layer beneath the skin) and visceral adipose tissue (fat surrounding internal organs)
Common side effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea), whilst serious but rare effects include pancreatitis and gallbladder problems
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Then there is the hormonal disruption