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a systematic review and meta-analysis found that after discontinuation of GLP-1 receptor agonists like semaglutide, weight regain occurs at an average rate of 0.4-0.8 kg per monthfour times faster than with behavioral weight management programswith participants often returning to near-baseline weights within 1.5-1.7 years and cardiometabolic benefits reverting to baseline within about 1.4 years, underscoring the need for prolonged therapy combined with lifestyle changes
Absolute or strong recommendations to avoid alcohol: History of pancreatitis: GLP-1 receptor agonists carry a small risk of pancreatitis, and alcohol is an independent risk factor for this serious condition
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Les premiers effets peuvent apparatre aprs quelques semaines dutilisation rgulire, avec une rduction progressive des fringales et une amlioration de la gestion des portions
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