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Via UBA, P63 containing the LIR or GIM structure domain attaches to ubiquitinated protein aggregates, mitochondria, etc., and the LIR or GIM structural domain binds to LC3 or GABARAP on the autophagy membrane and then forms autophagosomes

Theranostics (2020) 10:633760

They didn't start in a pharmaceutical labthey started with scientists studying the venom of the Gila monster

Carlsson SV, Barata PC, Bryce AH, George DJ, Gillessen S, Loeb S, et al

US Pharmacist

Sources of Glutathione Spinach, avocado, asparagus, and okra are all rich in glutathione, however, unlike other antioxidants, glutathione is not absorbed very well by the digestive system, so either eating glutathione-rich foods or taking glutathione-containing supplements are not effective ways to ensure an adequate source of this important antioxidant