Originally developed for managing type 2 diabetes, semaglutide GLP-1 has shown exceptional results in reducing body weight, leading to its approval for this purpose
The GLP-1 medications making the headlines are the synthetic versions designed to mimic natural GLP-1
However, tirzepatide may lead to fewer or less severe nausea symptoms compared to semaglutide, according to studies conducted by independent researchers, such as Phase 3 randomized controlled trials (RCTs) found in PubMed's electronic databases
Conclusions In this cohort study of adults with overweight or obesity who initiated GLP-1 RA therapy, most discontinued therapy within 1 year
Diabetologia 46 , 222230 (2003)
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