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The cryo-EM data were collected at Cryo-Electron Microscopy Research Center, Shanghai Institute of Materia Medica.

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Table 2 researches focus on the utilization of ammonia metabolism inhibitor

113 N-acetylcysteine N-acetylcysteine (NAC), a free radical-quenching compound made from the sulfur-containing amino acid cysteine, has been shown to reduce inflammation and oxidative stress, stabilize proteins and DNA, promote mitochondrial resilience, support antiviral immune activity, and promote vascular health

24 It catalyzes the last two steps of purine metabolism and produces uric acid