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Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. International Clinical Psychopharmacology, 2003

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This finding is in line with other previous studies conducted on different groups of older adults and reported significant improvement in the physical and mental fatigue with the L-carnitine supplementation in different intervention periods, different intervention doses, and different L-carnitine derivatives