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doi: 10.1016/j.aprim.2016.06.009

25 per 10 000 person-years), corresponding to a 39% higher relative risk

It should not be used during pregnancy or in people with kidney or liver diseases [11]

[8] [9] The ability of orforglipron to reduce blood sugar levels and body weight was judged favorable compared to dulaglutide

Advances in understanding hepatotoxicity mechanisms have led to identifying predictive biomarkers and hepatoprotective strategies, including antioxidants and non-invasive imaging techniques

The study proved that combination therapy (60 mg duloxetine + 300 mg pregabalin) was not significantly more effective than high-dose monotherapy (either 120 mg duloxetine or 600 mg pregabalin) in reducing pain after 8 weeks of intensified treatment