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To explore the T3 action in vivo, mice were rendered hypothyroid (MMI mice) by addition of 0.1% methimazole (M8506, Sigma) and 1% NaClO 4 (410241, Sigma) in their drinking water for 20 days as indicated 43
During the remodeling phase, cell proliferation, proper collagen deposition, and remodeling play crucial roles in enhancing tissue tensile strength and facilitating improved healing 75
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