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Promote the proliferation or increase the reproduction of pancreatic beta cells, which produce insulin GLP-1 receptor agonists may also restore the body's insulin-secretion function in the pancreas, which can contribute to improvements in glucose regulation and body weight reduction in those with diabetes

After one year, the change in eGFR was significantly higher in the bardoxolone methyl groups as compared with placebo (5.8 1.8 mL/min/1.73 m 2 for 25 mg vs

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1 mg = 1,000 mcg