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3-Methylglutaconic Aciduria, Type 1 During the catabolism of leucine, the 3-methylglutaconyl-CoA is converted to 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) via the action of the bifunctional enzyme, 3-methylglutaconyl-CoA hydratase

Ist zu wenig L-Carnitin im Krper vorhanden, werden die Fettsuren nicht mehr optimal in die Mitochondrien transportiert und knnen somit nicht in Energie umgewandelt werden

While the landscape of nutritional supplements in autism is complicated by mixed evidence and individual variability, there is promising research indicating that targeted dietary interventions and supplementation may modestly improve behavioral, sleep, and GI symptoms for some individuals

Muscle carnitine deficiency associated with zidovudine-induced mitochondrial myopathy

= 0.002, 6-fold in hypothyroidism, Sig

Any disruption of this process can result in delayed healing, persistent skin fragility, or hypertrophic scarring