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Starting weight also influences timeline perception: someone with 100+ pounds to lose may see steady progress for 12+ months, while those with 20-30 pounds to lose may reach goals within 4-6 months

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Moreover, emerging therapeutic agents are under investigation

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An interim analysis of a phase II study (FLIGHT-FXR) in biopsy-proven NASH patients with significant fibrosis (defined as stage 23 fibrosis) exhibited significant efficacy of tropifexor in hepatic steatosis reduction at 12 weeks after treatment

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