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This innovative approach has been shown to enhance the absorption and subsequent bioavailability of a variety of supplemental nutrients, such as vitamin D3, iron, and magnesium, suggesting that it could similarly improve the efficacy of oral B12 supplementation (2529)

While bacteriostatic water is favored for maintaining sterility over multiple uses, sterile saline is preferred when a sodium chloride solution is required or when the presence of benzyl alcohol is undesirable

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"Comparative Bioavailability and Utilization of Particular Forms of B12 Supplements With Potential to Mitigate B12-related Genetic Polymorphisms", Integrative Medicine: A Clinician's Journal (Encinitas)