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Ishihara H, Takagi T, and Kondo T, et al (2019) Association between immune-related adverse events and prognosis in patients with metastatic renal cell carcinoma treated with nivolumab Urol Oncol 37 (6) 355e21355e29 66

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Histological clarification by staged sections and confirmation of the precise tumor stage (pTis = melanoma in situ, Clark level I) is mandatory

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doi: 10.7554/eLife.50631CrossRefGoogle ScholarPubMed Chiu, K

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5 Conclusion Collectively, it can be concluded that MTX-induced hepatotoxicity is mediated, at least in part, through ER stress, which was confirmed by the reversal of MTX toxicity upon administration of 4-PBA and NAC

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