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Generally well-tolerated in animal studies with no major organ toxicity observed

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In sparsely spiny PV-positive interneurons from L2/3 of the visual cortex, synapses located on spines and on dendritic shafts both express CP-AMPARs and NMDARs, but the proportional contribution of NMDARs to calcium response in spines was about two times higher than at dendritic synapses (Sancho and Bloodgood, 2018)

Research Base Comparison Both compounds have substantial published research bases: AOD-9604

Griffith OW, Meister A

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