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Beyond energy production, NAD+ is also crucial for supporting DNA repair[1][2], regulating inflammation[2] and maintaining mitochondrial function[2]

This tightly regulated process, influenced by substrate availability, oxygen tension, and cellular energy demand, is crucial for cells with high energy requirements, such as cardiac myocytes, where mitochondria occupy 30% of the cell volume, and neurons, where they are dynamically distributed to synapses

Chen M, Li Y, Zhang L, Wang J, Zheng C, Zhang X

Took longer to arrive than expected

Hip dysplasia is a structural abnormality where the hip socket doesnt properly cover the ball of the thigh bone and can cause pain and instability

Additionally, RCTs will also assist researchers in identifying patient subgroups that are more or less tolerable to GLP-1RAs