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Broccoli extract, milk thistle, and alpha-lipoic acid are three nutrients shown to stimulate GSH production

Extra virgin olive oil, a fundamental component of this diet, contains bioactive polyphenolic compounds as hydroxytyrosol (HTyr) and oleuropein (OLE), known for their antioxidant, anti-inflammatory, and neuroprotective properties

Consumption of a single dose greater than 7 g in an adult and 150 mg/kg in a child is considered potentially toxic to the liver and kidneys due to the highly active metabolite, N -acetyl- p -benzoquinone imine (NAPQI)[5]

Because cellular iron output is mediated by FPN1 and polycupric ferrous oxide enzymes (such as ceruloplasmin), a decrease in the expression of FPN1 or ceruloplasmin can increase the sensitivity of cells to ferroptosis [29,30,31,32]

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