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GI side effects during the initial dose escalation phase are expected and typically improve with continued use

People with severe kidney disease should watch their potassium intake

An unused pen may be kept at room temperature (up to 86F or 30C) for up to 21 days

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Providers who have a clear escalation pathway, typically transitioning to injectable tirzepatide if drops prove inadequate, demonstrate patient-centered care

Insurers often enforce formulary restrictions or place limits on weight loss medications like tirzepatide, complicating access for patients