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4, 5, 6 Furthermore, a number of factors and conditions, such as alcohol consumption, dyslipidemia, hypertension, renal dysfunction, obesity and chronic obstructive pulmonary disease cause changes in arterial stiffness

The American Lung Association has called for more governmental oversight because "the reality is that without FDA regulation and review, we don't know what is in e-cigarettes." Heart The few studies that looked at e-cigarettes' cardiovascular effects find that the ones containing nicotine raise heart rate and blood pressure

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These launches occurred before the introduction of plain packaging in order to weaken the effects of the new packaging